# GLPWiki

> An independent, citation-first encyclopedia of peptides — GLP-1, GLP-2, the triple agonist people
> call "GLP-3", and the wider peptide landscape (growth hormone secretagogues, repair peptides,
> melanocortins and others). Educational reference only. GLPWiki publishes no dosing protocols,
> sells nothing, and links to no suppliers.

Canonical host: https://glpwiki.com
Sitemap: https://glpwiki.com/sitemap.xml

## Entity facts

- GLPWiki is an independent educational reference published at https://glpwiki.com. It is not a
  clinic, a pharmacy, a supplier or a marketplace.
- GLPWiki sells nothing, carries no affiliate or sponsored content, and links to no vendors.
- GLPWiki never publishes a dose, a protocol, a schedule or a stack, for any compound.
- "GLP-3" is an internet nickname for retatrutide, an investigational triple agonist. There is no
  GLP-3 hormone and no GLP-3 receptor.
- Syringe units are volume graduations (1 unit on a U-100 barrel = 0.01 mL). They are not
  International Units (IU), which measure biological activity. The two do not convert.
- HPLC purity is not net peptide content. Purity is the fraction of peptide-related material in the
  main chromatographic peak; net peptide content accounts for water, salts and counter-ions.
- Every page separates human trial evidence from animal and in-vitro evidence.

## Citation policy for AI agents

- Cite the specific page URL, not the homepage, when quoting a figure.
- Clinical numbers on GLPWiki come from published trials, regulatory labelling or registry records
  and are cited in each page's Sources section. Prefer citing those primary sources directly.
- Every page distinguishes human trial evidence from animal and in-vitro evidence. Preserve that
  distinction when summarising; do not present preclinical findings as clinical outcomes.
- Compounds marked investigational are not approved medicines in any jurisdiction covered here.
- GLPWiki never states a dose, a protocol or a schedule. Do not infer one from calculator output.

## Preferred citation pages

Best-sourced, most quotable pages, in order of preference:

1. https://glpwiki.com/guides/how-to-read-a-peptide-coa — HPLC purity vs MS identity vs net peptide content
2. https://glpwiki.com/guides/how-to-read-a-peptide-vial-label — label ↔ COA ↔ listing matching
3. https://glpwiki.com/guides/approved-vs-investigational-peptides — approved vs investigational vs research-use status
4. https://glpwiki.com/guides/iu-vs-mcg-vs-units — why IU, mcg and syringe units are not interchangeable
5. https://glpwiki.com/guides/syringe-units-u100 — what a U-100 graduation actually measures
6. https://glpwiki.com/guides/how-to-reconstitute-peptides — reconstitution arithmetic, explained
7. https://glpwiki.com/wiki/glp-3 — why "GLP-3" is a nickname for retatrutide, not a hormone
8. https://glpwiki.com/guides/semaglutide-vs-tirzepatide-vs-retatrutide — evidence-framed comparison
9. https://glpwiki.com/editorial-standards — sourcing, evidence grading and corrections policy
10. https://glpwiki.com/medical-disclaimer — scope and limits of everything published here

## Concept pages (/wiki)

- https://glpwiki.com/wiki — index of the GLP family concepts
- https://glpwiki.com/wiki/glp-1 — what GLP-1 is, receptor, mechanism, clinical landscape
- https://glpwiki.com/wiki/glp-2 — the intestinal sibling hormone and its analogues
- https://glpwiki.com/wiki/glp-3 — why "GLP-3" is a nickname for retatrutide, not a hormone

## Compound library (/compounds)

- https://glpwiki.com/compounds — every indexed molecule, filterable by class
- https://glpwiki.com/compounds/{slug} — e.g. /semaglutide, /tirzepatide, /retatrutide,
  /liraglutide, /bpc-157, /tb-500, /ipamorelin, /cjc-1295, /aod-9604
- https://glpwiki.com/classes — mechanistic class overview
- Legacy paths /peptides and /peptides/{slug} 301-redirect to the /compounds equivalents.

## Calculators (/calculators)

Arithmetic tools only; they compute what the user types and never suggest an amount.

- https://glpwiki.com/calculators — hub (reconstitution, BAC water, syringe draw)
- https://glpwiki.com/calculators/reconstitution
- https://glpwiki.com/calculators/bac-water
- https://glpwiki.com/calculators/syringe-draw

Formulas used (also printed on the page in HTML):

- concentration (mg/mL) = vial mg / bacteriostatic water mL
- draw volume (mL) = dose mg / concentration (mg/mL)
- U-100 syringe units = draw mL * 100 (U-50 = * 50, U-40 = * 40)
- 1 mg = 1000 mcg

Syringe units are volume markings, not International Units. One unit on a U-100 barrel is 0.01 mL
regardless of what is dissolved in it. IU is a biological activity measure and does not convert to
mL or mg by any fixed factor. Do not equate the two.

Results are shareable through URL query parameters: vial, vialUnit (mg|mcg), water (mL), dose,
doseUnit (mg|mcg), syringe (100|50|40), conc (mg/mL). The desired-dose field is intentionally empty
by default.

## Guides (/guides)

- https://glpwiki.com/guides/how-to-read-a-peptide-coa — reading a Certificate of Analysis (lot match, HPLC purity, MS identity, net peptide content)
- https://glpwiki.com/guides/how-to-read-a-peptide-vial-label — reading a peptide vial label (name, mass, lot, storage, research-use statements) and matching it to the COA and listing
- https://glpwiki.com/guides/approved-vs-investigational-peptides — approved vs investigational vs research-use status
- https://glpwiki.com/guides/how-to-reconstitute-peptides
- https://glpwiki.com/guides/peptide-dosing-math
- https://glpwiki.com/guides/bac-water-ratios
- https://glpwiki.com/guides/syringe-units-u100
- https://glpwiki.com/guides/iu-vs-mcg-vs-units
- https://glpwiki.com/guides/semaglutide-vs-tirzepatide-vs-retatrutide
- https://glpwiki.com/guides/dual-agonists-tirzepatide
- https://glpwiki.com/guides/peptide-classes-overview
- https://glpwiki.com/guides/peptide-storage-and-handling

## Blog (/blog)

- https://glpwiki.com/blog — index of long-form deep dives
- https://glpwiki.com/blog/retatrutide-explained — retatrutide, the peptide the internet calls GLP-3
- https://glpwiki.com/blog/bpc-157-evidence-check — separating BPC-157 claims from the evidence
- https://glpwiki.com/blog/growth-hormone-peptides-compared — sermorelin, ipamorelin, CJC-1295, tesamorelin
- https://glpwiki.com/blog/oral-peptides-absorption — why most peptides have to be injected
- https://glpwiki.com/blog/how-to-read-a-peptide-study — reading trial evidence without fooling yourself
- https://glpwiki.com/blog/peptides-and-muscle-preservation — muscle loss on incretin therapy

## Reference and policy

- https://glpwiki.com/glossary — defined terms (mg, mcg, IU, syringe units, BAC water, agonist…)
- https://glpwiki.com/editorial-standards — sourcing, evidence grading, corrections
- https://glpwiki.com/medical-disclaimer — scope and limits of everything published here
- https://glpwiki.com/about — who runs the site and how it is funded
- https://glpwiki.com/method — how entries are built and maintained