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NEURO & COGNITIVE · RESEARCH

Selank

ALSO KNOWN AS · Tuftsin analogue TP-7

A synthetic analogue of the immunopeptide tuftsin studied as a non-sedating anxiolytic. Russian trials report anxiolytic effects comparable to benzodiazepines without dependence; independent replication is lacking.

Mechanism

Selank appears to stabilise enkephalin levels by inhibiting their degradation and to modulate GABA-A receptor expression, alongside effects on serotonin turnover.

PRIMARY SOURCES

  1. 01Selank anxiolytic activityBulletin of Experimental Biology and Medicine

Educational reference only. Trial figures are protocol-condition means, not individual predictions. Investigational compounds are not approved medicines and have no legitimate consumer supply route.